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Thyroid 26(S1):P-1-A-129, 2016

Binding of GLP-1 to GLP1R has multiple effects, including enhancing insulin secretion from pancreatic beta cells in response to glucose, increasing insulin expression, preventing beta-cell apoptosis, promoting the formation of new beta cells, reducing glucagon secretion, slowing down stomach emptying, promoting satiety, and improving glucose disposal in peripheral tissues

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The TB-500 fragment retains the critical actin-binding and cell-migration-promoting activities of the full-length TB4 molecule, making it the predominant research form used in pre-clinical peptide studies